Champions and leaders Girondins Bordeaux are likely to be without goalkeeper Cedric Carrasso (pictured) and central defender Marc Planus when they visit promoted Boulogne on Saturday.
Both sustained thigh injuries in a 1-1 Champions League draw at Juventus on Tuesday. "It seems very complicated", coach Laurent Blanc told reporters when asked whether the pair would be fit to play.
Olympique Lyon's France midfielder Jeremy Toulalan impressed in central defence in a 1-0 Champions League win over Fiorentina on Wednesday.
With Mathieu Bodmer still suffering from a groin problem, he could play in that position again when second-placed Lyon visit Paris St Germain on Sunday.
PSG will miss arguably their best player in Benin midfielder Stephane Sessegnon, suspended after being sent off for a dangerous challenge in a 2-0 defeat at Monaco last weekend.
Olympique Marseille president Jean-Claude Dassier has stirred controversy by saying he would not be an "African-style president", which has irritated former OM president Pape Diouf , who was born in Chad and grew up in Senegal.
"I can admit my statements were clumsy but they were not aimed at Pape Diouf," Dassier, whose team host surprise package Montpellier on Saturday, told reporters.
Marseille will welcome back defender Laurent Bonnart, who has recovered from the groin injury that kept him out of Tuesday's 2-1 home Champions League defeat by AC Milan.
Promoted Montpellier, in third place two points off the pace after a strong start, have said they face up to seven months without 19-year-old midfielder Remy Cabella, who has undergone surgery on ruptured knee ligaments.
Nancy, visiting Lorient on Saturday, have to make to without Brazilian defender Andre Luiz, who was suspended for three matches for head-butting Toulouse midfielder Etienne Didot last weekend.
