The Spanish giants were caught cold by Borussia Dortmund in their semi-final first leg last week, when, despite being one of the favourites to step out at Wembley on May 25, they were left on the brink of a surprise elimination.
Since their return to Spain, Real have delved into their extensive archives to dig up past examples of heroic fightbacks to convince fans and players of Tuesday's second-leg possibilities.
Real have overturned an identical scoreline once before in Europe's elite club competition, against Derby in 1975.
"The games against Derby and Borussia Monchengladbach [a similar comeback in the UEFA Cup] were incredible games," Santillana told sports daily Marca.
"The Bernabeu, if you light the match, burns everything."
Much of Real's hope of a comeback rests with Cristiano Ronaldo, who missed the city derby against Atletico Madrid in La Liga on Saturday, when a second-string side triumphed 2-1 at the Calderon.
Ronaldo is the Champions League's leading scorer with 12 goals and has netted 51 times in 50 games for his club so far this season, but picked up a muscle problem in Dortmund and trained apart from the group again on Sunday.
The second leg is also a challenge to Real coach Jose Mourinho's prestige as failure to progress from a third successive Champions League semi-final would test the patience of club president Florentino Perez.
With the La Liga title about to fall to Barcelona, and Real's European campaign hanging by a thread, next month's King's Cup final might end up representing Mourinho's last chance for major silverware this season.
"With 10 changes it was not very easy but we are pros and need to accept it," captain Sebastian Kehl said on Saturday.
"We wanted to win to secure second spot and fill up on confidence ahead of Tuesday."
