The teenage forward - a reported transfer target for Chelsea and Real Madrid - has been the inspiration behind Santos' run to the final, with the club having started as tournament outsiders in February.
Not even the ash spewing from a Chilean volcano that has disrupted air travel in the southern cone of South America for more than a week has upset the Brazilian team's resolve.
"There was anxiety over not knowing how we were going to get there but nothing will stop our will to be champions," Neymar told reporters as the squad left for the game in Montevideo.
"The match is going ahead," Nestor Benitez, spokesman for Conmebol, staunchly declared.
"Santos are flying to Montevideo where the airport has been opened, and so are the match officials. Let's hope it's a great occasion after so much uncertainty," Benitez told Reuters.
Pele, who helped Santos win South America's equivalent of the European Champions League in 1962 and 1963, told the Uruguayan daily El Pais: "I love Santos and want them to be champions, but in this match there are no favourites and any of the two can win".
The footballing great added that playing a Uruguayan team "is very difficult because they are warriors and they battle up to the last minute in or outside Uruguay."
Another key factor in Santos' improvement has been the arrival in March of coach Muricy Ramalho who is looking for his first Libertadores crown.
