Mauro Icardi scored twice as Inter put in a dominant performance to win 4-0 at Udinese and extend their lead at the top of Serie A to four points.
Icardi, recalled to the side after being dropped for last weekend's 1-0 victory over Genoa, put Inter ahead midway through the first half and Stevan Jovetic doubled the lead.
Inter had to wait until the closing minutes for a third goal, Icardi on target again with a powerful finish for his sixth goal of the season, before Marcelo Brozovic completed a fine team performance with a brilliant curling strike.
With Scudetto rivals Napoli hosting Roma and Fiorentina travelling to Juventus on Sunday, Roberto Mancini's men are now in a strong position at the summit.
Palermo beat Frosinone 4-1 at home to climb away from the relegation zone. Edoardo Goldaniga and Franco Vazquez put the hosts 2-0 up within the first 17 minutes, but Paolo Sammarco struck back before the break.
Aleksandar Trajkovski made it 3-1 with substitute Alberto Gilardino adding late gloss to the scoreline.
Luca Rossettini's injury time strike gave Bologna a 1-0 win at Genoa, with both sides having a man sent off in the last 10 minutes.
Diego Perotti saw red for the hosts before Amadou Diawara was given a second yellow card shortly before the final whistle.
Elsewhere, Sassuolo's home game against Torino was postponed due to heavy fog.
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