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The duo form part of an otherwise experienced contingent for Wednesday's friendly, as preparations for the 2014 FIFA World Cup step up a gear.
Rafa has displayed impressive form since joining Braga from Feirense in the close season, scoring three goals in 18 league appearances.
Edinho is included among Portugal's forwards following his recent loan switch from Braga to Kayseri Erciyesspor in Turkey, while Lyon's Miguel Lopes and Inter loanee Rolando are among those returning to the fold.
A hamstring injury rules out Manchester United's Nani, while Real Madrid's Cristiano Ronaldo will once again lead the side.
Forwards: Rafa (Braga), Ivan Cavaleiro (Benfica), Edinho (Kayseri Erciyesspor), Hugo Almeida (Besiktas), Cristiano Ronaldo (Real Madrid), Silvestre Varela (Porto).
