U.S coach Bob Bradley will be without suspended striker Robbie Findley and is expected to bring in Edson Buddle in attack alongside Jozy Altidore.
But Bradley is also likely to field a different midfield for the third successive match as he searches for a way to end a frustrating habit of conceding early goals.
Maurice Edu, an effective second-half substitute, could start alongside Bradley's son Michael.
"In the second half of the game when we had got to push the game, I felt that the work of the whole team, the work of the midfielders, to push, close down, try and win the ball back was really good. Those were all positives," he said.
"As you get ready for Algeria you look hard to see what that game will be like and now you assess where we are as a team with injuries, fitness and fatigue and make decisions," he said.
Although Dempsey has stated he is happiest on the left, where he can cut in onto his right-foot, he can be effective as a second striker and Holden's crossing ability could be crucial with two big strikers to aim for in the area.
"It shows even when you have a talented attacking team like England, when you play against a team that's organised, with numbers behind the ball, then breaking them down, making the right play, and getting a goal is still not always easy," said Bradley.
"Against England we proved ourselves to be up to the task and we even had chances to win the game. We showed the best of ourselves and that's how we'll need to play against the United States to win and qualify for the last sixteen."
