Borussia Dortmund and Bayer Leverkusen recorded big wins to progress to the round of 16, while Borussia Monchengladbach saw off Schalke.
Bochum Bundesliga side Stuttgart were dumped out of the DFB-Pokal on Saturday after losing 2-0 at second-tier club Bochum.
Holders Bayern Munich will start their DFB-Pokal defence with a trip to 3. Liga side Preussen Munster on Sunday.
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