Diego Simeone's men offered a Hollywood ending to what has been one of the most exciting title races in recent years, with a squad lacking the global stars of both Real and Barca overcoming all the odds to land their first title since 1996.
While Diego Costa has shot to prominence as the spearhead of Atletico's attack this season, Simeone has not been able to call on the likes of Cristiano Ronaldo, Gareth Bale or Lionel Messi.
However, Simeone has proven that a combination of tactical acumen, talent and - perhaps above all - hard work can trump the mega-spending that is commonplace at the Bernabeu and Camp Nou.
That is not to say Simeone has a bunch of also-rans at his disposal - the likes of Costa, Thibaut Courtois and Koke would grace any of Europe's premier clubs - but they have adopted a less extravagant approach than Real and Barca.
And that is why the Argentinian indicated recently that his side have become everyone's second favourite team in Spain for their remarkable efforts this season.
The prospect of Atletico denying Spanish football's two powerhouses both at home and abroad felt far-fetched when 2013-14 Liga champions Barca got their title defence off to a flyer by hammering Levante 7-0 on the opening day of the season.
Real then entered the mix - taking advantage of their rivals' goalless draw in January to move within three points of the top pair.
Carlo Ancelotti's men did not lose a league game from the start of the year until March's Clasico defeat but, from then on both they and Barca stuttered as Simeone's men closed in on the title - while also knocking Barca out of the Champions League at the quarter-final stage.
Atletico's failure to beat both Levante and Malaga in their third and second-last league games of the season set up a grandstand finale, as they visited the Camp Nou on the final day of the campaign needing to avoid defeat to end their 18-year title drought.
However, Diego Godin's towering header early in the second half earned the visitors the point they required - with the Camp Nou faithful even showing their gracious appreciation of Atletico's effort by applauding their opponents at the final whistle.
Regardless of whether their success proves a flash in the pan - as was the case with the fleeting success enjoyed by Deportivo and, to a lesser extent, Valencia in the early 2000s - Atletico's victory re-energises a league that had grown slightly stale at the top.
The next test for Simeone and his players is to regularly compete with the big two - but for now, Atletico can bask in the most special and unexpected triumph of the European football season.
