"Gareth has had a bit of a hamstring [problem], hopefully he should be OK," manager Harry Redknapp told reporters at the club's training ground on Friday.
Bale missed Wales' friendly with Costa Rica on Wednesday with British media reports suggesting he had suffered a grade one tear to his hamstring training for the game, played in honour of the late Wales manager Gary Speed.
"He hasn't even got a tear in his hamstring, it's just a bit tight, but he should be OK. It shouldn't be a problem," said the Spurs boss.
Bale was due to train with Spurs on Friday as they attempt to bounce back from last Sunday's shattering 5-2 loss at rivals Arsenal.
"Rafa is hopefully going to train today, he feels a lot better," he said.
Third-placed Tottenham host United, who are second, looking for their first win against Sir Alex Ferguson's side since 2001.
Although Spurs were heavily beaten at Arsenal, they remain seven points ahead of their North London rivals in the race for third place and an automatic qualifying spot for next season's Champions League.
