"We want to show who should be sitting top of the table -- and that is Bayern," defender Philipp Lahm told the club's website (www.fcbayern.t-home.de). "We have to set a mark."
Hoffenheim, who only won promotion to the top flight this year, have been phenomenal, scoring three or more goals in 10 of their 15 league games.
But Bayern coach Juergen Klinsmann is confident his in-form team will prevail in front of a sell-out home crowd at the 69,000-seat Allianz Arena.
"We want to have a good game and bag the three points," he said. "The time has come for Bayern to take over the lead.
Bayern midfielder Mark van Bommel and defender Martin Demichelis are expected to return to the squad after missing last week's match through illness and injury.
Tim Borowski, who sat out a day of training after picking up a minor injury last week, will also be fully fit, the club said.
Bayern have said fan interest for the match has been so high they could have sold as many as 150,000 tickets.
Hoffenheim, three points clear of second-placed Bayern and with a superior goal difference, will be no pushover though.
With the league's most effective attack and the Bundesliga's top scorer in Vedad Ibisevic, the season's surprise package do want to play a supporting role.
"Bayern are a great team but they are beatable," said Bosnian Ibisevic, who has struck 17 times in 15 matches.
"We are not going to Munich just to look at the stadium. We are going there to win."
On Saturday (1430), third-placed Hertha Berlin, four points off the pace, visit Schalke 04 while Bayer Leverkusen, in fourth after their 2-0 defeat by Bayern last weekend, are away to one-from-bottom Borussia Moenchengladbach. (Writing by Karolos Grohmann in Athens, editing by Rex Gowar)
