The 27-year-old Czech Republic international, who had his nose broken by two Cologne fans in an incident outside a nightclub earlier this month, sustained further damage despite playing with a carbon face mask in Saturday's 1-0 win over Hannover 96.
"His shattered nasal bone shifted further despite the mask," Leverkusen said in a statement on Monday before adding he would be out for 10 days.
Leverkusen, who are fifth in the table, take on Nuremberg on Saturday.
Get the best features, fun and footballing frolics straight to your inbox every week.
Thank you for signing up to Four Four Two. You will receive a verification email shortly.
There was a problem. Please refresh the page and try again.