A 1-0 defeat by Norway in Oslo on Saturday in their latest preparatory match means South Africa have now lost seven of their last eight internationals and show little sign of becoming anything but a minor sideshow at next year's finals.
Santana said he was still confident in his position and of making progress on delivering a competitive side.
Saturday's performance against Norway would not have helped his cause with South Africa creating few chances and being fortunate not to have been more severely punished for several defensive lapses.
But Santana said of the friendly: "These matches are designed for training. When we get to the World Cup it will be a different game."
Portsmouth defender Mokoena, closing in on 100 caps for his country, told Reuters: "It's been difficult take all these defeats. All of us are angry about not getting results."
