Talks between the players union (AFE), which last week called the strike for the first two rounds of matches in the top two divisions, and the professional football league (LFP), which represents the 42 clubs affected, failed to prevent the action.
European champions Barcelona and Real Madrid, the two richest clubs by revenue in the world, had been due to start their campaigns on Sunday.
At the heart of the dispute is the union's demand that an emergency fund be set up to cover wages that have not been paid to players at clubs that have gone into financial administration.
The union says around 50 million euros is owed to 200 footballers from the end of last season, and the league's proposed 40 million euro fund is not enough to cover a growing problem.
"We have the best football in the world, but it is run very badly. The league has failed to control the situation with the clubs," Jose Maria Gay, an accounts professor at Barcelona University, told Reuters.
"Winning Euro 2008 and the World Cup earned Spain a great deal of goodwill, it helped open doors for us. But a strike because we can't pay our players will generate a lack of confidence in Spain as a whole.
"It would be a good time to use the situation to restructure Spanish football. It can't carry on as it is. They need to get out of the clouds and back down to earth."
Analysts say the rules surrounding the "Ley Concursal" process have been used as an easy way for clubs to get out of their predicament, to preserve their league status, and to allow them to continue pursuing their irresponsible practices.
"They have no shame," Getafe president Angel Torres told sports daily Marca.
"If they are showing so much solidarity, why don't they he
