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The Spain international has been trying to shake off the injury for several weeks and it forced him off in the second half of Barca's 2-1 La Liga victory over Valencia on Saturday.
"He finished (the Valencia game) with some discomfort and since then he's been improving," Guardiola told a news conference ahead of Wednesday's Champions League Group D clash at the Nou Camp.
"He is unique in many ways but there are alternatives and several players who can do a good job," he added.
"Xavi is extremely important for how he plays and how he dictates play," the Argentina international said.
"In any case, we have enough reserves if he doesn't make it as we have a very strong squad," he added.
