The 22-year-old Borussia Dortmund player has also been ruled out of his country's September 6 friendly away to Poland.
"He picked up an ankle injury at the weekend and that now forces him to take a break, so we will have to do without him," Low told reporters on Tuesday.
Germany top qualifying Group A with seven wins out of seven and a maximum 21 points. A win against the Austrians will see them through to next year's tournament, which is being co-hosted by Poland and Ukraine, with two games to spare.
"So we have 18 in-field player and three goalkeepers. For these two games it will suffice," Loew said.
"We were confronted with the fallout from this book non-stop in the past days," Low said. "I personally told Philipp I do not think it is proper as a current player to judge coaches in public. You should not do this.
"I think this is unfortunate but we are all of the opinion that as a whole the book did not reveal any internal issues from inside the team. I hope the issue for us is now closed and we can focus on our next tasks, the important ones."
Lahm, who has since apologised for any "misunderstanding" his book may have caused, said no player on the team had a problem with what he had said.
"Obviously the last few days were not comfortable. I did not expect such a reaction. For me it is a great honour to play for Germany and I have not felt anything from the other players," Lahm said.
"The coach told me not to talk about other coaches and I will not to do this again.
"What we want to focus on now is to seal qualification and on Friday we have a huge chance at home against Austria to achieve this.
"It has never happened before that a German team wins all qualifiers. We will do everything we can on Friday to give the Austrians no chance."
