Pep Guardiola's men have been in imperious form this season, dropping points in just two of their 20 league matches, but one of those occasions came at Freiburg in August and the strugglers will be hoping to upset the form books for a second time.
It is a mammoth ask of a Freiburg side that have won just four times all season, against a Munich team that has gone a record 45 matches without defeat in the league, a run that stretches back to a 2-1 reverse to Bayer Leverkusen in October 2012.
Guardiola's side boast the best attack in the division, with 53 goals to their name, the meanest defence - which has conceded just nine times this season - and they enjoy a 100 per cent record on home soil in the league this term.
Bayern's Bastian Schweinsteiger, absent since November with an ankle injury, returned in Wednesday's 5-0 thrashing of Hamburg in the DFB-Pokal.
"It's really good to be back in the side and to get such a great reception," he said.
"There are some crucial games coming up where it may turn on minor things. Obviously, we're very confident at the moment.
"We know what we can do and what level of performance we're capable of producing. But now we've got to show it on the pitch."
