Brazil will be well represented in the quarter-finals of the Copa Libertadores after Botafogo and Santos progressed, while San Lorenzo prevailed on penalties.
After Atletico Mineiro and Palmeiras were eliminated on Wednesday, Botafogo and Santos joined Gremio in the last eight thanks to respective victories over three-time champions Nacional and Atletico Paranaense.
The match, however, was marred by four late red cards – three of those to Nacional players.
It will be an all-Brazilian affair in the quarters of South America's premier club competition when Botafogo face Gremio, starting in September.
Bruno Henrique's winner with 12 minutes remaining in Sao Paulo confirmed a meeting with Ecuador's Barcelona.
Osbaldo Lastra's 48th-minute goal levelled the tie 1-1 on aggregate and forced spot-kicks in Buenos Aires.
