The Frenchman tweaked his knee in last Sunday's Community Shield when United came from behind to beat neighbours Manchester City 3-2 at Wembley.
"We'll give him until tomorrow but he is doubtful," Ferguson told a news conference ahead of Sunday's trip to West Brom.
"Chicharito is still, I would say, 10 days away from taking part in any football," said Ferguson. "It's not a concern, just a precaution given the fact had a concussion a couple of years back."
"We had the worst record away from home in the Premier division and the best home record in the Premier division so what do we do about it? I don't know. It was surprising the number of points we dropped away from home I must say," Ferguson said.
"I agree with you [that we can't bank on our home form this season]."
Whether his young players have done enough to earn first-team spots remains to be seen but they are certainly on Ferguson's radar.
"We've got a strong squad... I think picking a team is maybe easier with the second-half performance last week in some ways but we still have to respect the experience of the ones who came off at halftime," the manager said.
"Probably the fact we won so well last Sunday [has made us favourites]," said Ferguson before pointing out that Manchester City, Chelsea, Liverpool and Arsenal were all contenders.
"We used to talk about top four but now we talk about top six really."
