Newport County knocked Middlesbrough out of the FA Cup to set up a fifth-round tie at home to Premier League champions Manchester City.
Boro boss Tony Pulis endured a miserable return to Newport as his Championship promotion hopefuls were beaten 2-0 in Tuesday's replay by the League Two side.
In heavy rain at Rodney Parade, Robbie Willmott opened the scoring for Newport with a long-range strike that Boro goalkeeper Dimitrios Konstantopoulos should have kept out.
But there was nothing the 40-year-old Greek could do about the clincher as a right-wing corner routine produced a stunning second Newport goal.
Willmott's low delivery fooled the Boro defence and Padraig Amond met the ball with a superb first-time finish that sent the ball spinning into the top corner for his fourth FA Cup goal of the season.
Newport took Tottenham to a fourth-round replay last season and Michael Flynn's side now have a date with City to look forward to later this month.
Wolves had to come from behind at Shrewsbury Town to force a replay and they were again pushed hard by the League One strugglers in the Molineux return.
Matt Doherty's second-minute goal opened the scoring but goals from James Bolton and Josh Laurent put Shrewsbury in front in the tie once more.
Doherty levelled in first-half added time, though, and Wolves edged through 3-2 thanks to a winning goal in the 62nd minute that was made by Doherty and scored by Ivan Cavaleiro.
Second-half goals from Nahki Wells and Matt Smith earned Queens Park Rangers a 2-0 home win over Portsmouth, while Brentford prevailed 3-1 against Barnet in the battle of the Bees.
Last-16 ties will be played over the weekend of February 15 to 18, with Chelsea hosting Manchester United in a repeat of last year's final in the tie of the round.
FA Cup fifth round draw in full:
Bristol City v Wolves
AFC Wimbledon v Millwall
Doncaster Rovers v Crystal Palace
Newport County v Manchester City
Chelsea v Manchester United
Swansea City v Brentford
Queens Park Rangers v Watford
Brighton and Hove Albion or West Brom v Derby County
