Cesare Prandelli's men have not tasted victory since a 2-1 triumph over Czech Republic in a FIFA World Cup qualifier in September, but will be heavy favourites to end a six-game winless run on Wednesday.
They take on a Luxembourg outfit ranked 112th in the world, 103 places lower than the esteemed four-time world champions.
Italy's latest attempt to secure a win ended in a 0-0 draw with Republic of Ireland on Saturday, with news of an injury to Riccardo Montolivo coming as a real blow.
Prandelli confirmed his final 23-man party on Sunday, with Giuseppe Rossi the most notable exclusion.
Rossi battled back from a serious knee injury sustained in January to gain a place in Italy's provisonal squad, only to then be omitted.
"I can't imagine what Riccardo is going through at the moment," said Verratti. "His injury has shaken us all up a bit.
"But now we have to take this opportunity that has been offered to us by the coach.
"The World Cup is the World Cup – there's going to be great enthusiasm wherever we go. It's going to be exciting to play there.
"To represent the country in South America is going to be a real source of pride for me."
Wednesday's match in Verona represents a golden chance for Italy to gain confidence ahead of their departure for Brazil, against a Luxembourg side that has won only two of their previous 19 fixtures.
Luxembourg's most recent victory came on September 10 - also the same date Italy last won - when Mathias Janisch's late goal secured a 3-2 success over Northern Ireland in a World Cup qualifier.
And Luc Holtz's men will have it all to do if they are to avoid a similar beating at the hands of an Italy side desperate to return to winning ways before their World Cup campaign begins in earnest.
