Manchester United playmaker Henrikh Mkhitaryan limped out of Wednesday's Europa League clash with Saint-Etienne after opening the scoring.
The Armenia international lasted less than half an hour of the last-32 second-leg meeting at the Stade Geoffroy-Guichard, with his 16th-minute strike putting them 4-0 up on aggregate.
But just nine minutes later he withdrew from the action, walking straight down the tunnel while appearing to gesture towards his hamstring.
The injury gives Jose Mourinho a potential headache ahead of Sunday's League Cup final with Southampton at Wembley.
PIC: The moment Mkhitaryan put us ahead before being withdrawn due to injury. February 22, 2017
Get the best features, fun and footballing frolics straight to your inbox every week.
Thank you for signing up to Four Four Two. You will receive a verification email shortly.
There was a problem. Please refresh the page and try again.