The visitors come into the clash at Turf Moor on the back of a torrid run of form, with only two points to show from those eight outings, after taking 10 points from their first four league encounters this term.
Villa came close to ending their winless sequence on Monday, but Nathaniel Clyne's 81st-minute equaliser rescued a 1-1 draw for second-placed Southampton at Villa Park.
"Everybody is the same. They are doing well but no-one will return," said Lambert on Thursday. "It's more or less the same as Monday against Southampton.
"It's Vlaar's calf, not what is was the last time. It's a strain. It's the same calf but a different part.
"Philippe has a calf problem and it's Christian's last game banned. Fabian is doing well in his rehab but is a few weeks away. Nathan will be out for longer.
"Six players out for our club is hard. If you lose six players even if you're a top club it's a big, big chunk."
The goalkeeper has been an ever-present in the league for Sean Dyche's men this season, and his first clean sheet in six matches helped the team to their maiden win of the campaign, a 1-0 triumph over Hull City before the international break.
"That’s something we've talked about," he told reporters. "It's something we try and use. You can be successful, I think, if you use that underdog tag.
"It's difficult for teams, they don't quite know what to expect. We're new into the league so we like to think we're going to make it difficult for everyone.
"It's always nice to prove the doubters wrong. We've got internal expectation, but externally there is probably isn't an awful lot.
"It depends which way you look at it. We try not to let it affect us. We've still got to go and do our job and we go about our business well and the manager is great for that."
