With Morgan De Sanctis, Kostas Manolas, Radja Nainggolan and Alessandro Florenzi starring, Roma have won their first three league games without conceding a goal.
Extending that run at Parma will not be easy, though, with Cassano - who left Roma in 2006 after five years at the club - having scored three goals in his last two games.
"We tried to reduce the gap from Juventus over the summer," said Garcia, whose side finished 17 points behind the Turin giants in 2013-14. "We've started well but we have to stay focused."
Juventus, for their part, have never suffered defeat by Cesena in their eight encounters. With Paul Pogba and Carlos Tevez thriving, Massimiliano Allegri's team are hot favourites to make it four wins from four.
"The indications from the start of the season are that it is between Juve and Roma," said Juventus director general Giuseppe Marotta, before praising his coach: "He is a winner, a great leader."
Allegri chose to deflect the plaudits to his team. He said: "Our positive start has been deserved by my players. When you have talented players as I do, everything is easier. However, we still have room for improvement."
Verona, two points off the pace, are at home to Genoa in a match in which the hosts' 37-year-old striker Luca Toni will face one of his 14 former clubs, while seventh-placed Sampdoria entertain struggling Chievo.
Milan, in fourth, are away to second-bottom Empoli in Tuesday's only fixture. Despite a 1-0 loss at home to Juventus on Sunday, Milan coach Filippo Inzaghi will have taken encouragement from another fine performance from Jeremy Menez, and Fernando Torres' return from injury as a second-half substitute.
Rafael Benitez is under pressure after his Napoli team, who face Palermo, were eliminated from the UEFA Champions League qualifying round and have suffered back-to-back 1-0 losses in Serie A.
