Ferguson wants to keep the 40-year-old, who is retiring at the end of this season, fresh for the May 28 Champions League Final against Barcelona and hopes his team can pick up the point they need for the domestic title without him.
"I'm going to rest Edwin van der Sar tomorrow given the programme he's been through in the last few weeks," Ferguson, seeking a 12th Premier League title with the club, told a news conference on Friday.
"He's played every game... we have an opportunity to give him a break."
"We're going to play our strongest team. It's a big game. It's always a difficult game at Blackburn," he said. "They are also fighting, I think they probably need a point."
"We've got to give him a chance (to get back in time). He is back training every day, he's over his virus he had," said Ferguson, adding that Fletcher had come through more than an hour in a reserve game against Blackburn this week.
"It's a matter of getting the strength and speed to his game and we have some games to try and do that. I think he'll go very close, the boy's got application and the desire to do it and hopefully we can get him there."
