Veteran midfielder Egidio Arevalo said defending champions Uruguay are back to retain their Copa America title.
Uruguay claimed a 15th Copa America title after trumping Paraguay four years ago, with the South American giants led by Luis Suarez and Diego Forlan.
"We come with the same dreams and desire to get it [the Copa] back," Arevalo was quoted as saying.
"Even though the squad has new faces, the desire and enthusiasm to be champions still remains intact.
"On the field, we become strong and fight for every title we want."
Saturday's opponents Jamaica - competing in the Copa America for the first time in their history - are expected to make a swift exit in the 44th edition of South America's premier international tournament.
Coach Wilfried Schafer acknowledges Jamaica's inferiority but believes the CONCACAF nation are capable of an upset.
"I would say that we can only win through crosses, because we have very tall people, or that Uruguay will not have a good day," the German said.
"But if we play with a lot of discipline, with speed and close spaces, we can improve ourselves."
