The Africa Cup of Nations Group E qualifier sees two sides who played against each other just last week do battle again.
Saturday's clash was shifted to Casablanca due to the breakout of the ebola virus in West Africa and ended in a 1-1 draw in what was classed as a home match for Guinea.
Gyan fired Ghana ahead in the 27th minute with his first goal of the campaign, but Ibrahima Troare ensured both sides would share the spoils with an 81st-minute equaliser.
"Our objective was to get all six [points] in these two matches but we were quite disappointed that things didn't go as planned in Morocco," Gyan told reporters.
"Though we are quite disappointed we didn't win the match, it is an important point for us and a win in Tamale will push us further in the group.
"We've heard about the enthusiasm in Tamale ahead of the match.
"And we are very determined to put smiles on the fans who will be at the stadium, and all Ghanaians."
Ghana will again be coached by caretaker Maxwell Konadu, who is the nation's Under-23 coach.
One win and two draws from three matches represents a decent start to qualifying, though, and Ghana are one point ahead of Uganda and Guinea.
All of their five goals have been scored by different players, which is a positive sign for a side so often reliant on Gyan.
