With Manchester United crowned champions, Manchester City guaranteed second spot and all three relegation victims already decided, the focus is on the Champions League places with Chelsea on 72 points, Arsenal on 70 and Spurs on 69.
Third place earns automatic passage to the group stage of Europe's elite club competition, while fourth place means a ticket to the third qualifying round.
Last year Arsene Wenger's Arsenal side snatched third on the last day of the season with Spurs ending up fourth, their misery compounded by the fact they missed out on the Champions League as Chelsea took the final English spot as European champions.
This time, Andre Villas-Boas's side are the chasers and will be hoping for a change in fortunes when they host Sunderland as they could end up in the frustrating position of notching their highest ever Premier League points total of 72 and still miss out.
"All we can do is win our games and it's important for us to keep believing," defender Jan Vertonghen said on the club's website. "We would have to do that anyway on Sunday, so let's hope we can."
"There will be nerves again [at Newcastle], but we have dealt with nerves for a long, long time now," Wenger told Arsenal Player.
"It is natural of course, because it shows that [the players] care but this team is on an exceptional run and has an exceptional spirit.
"We have 70 points, the target is 73, so let's just go with the spirit and desire we have and I think we can do it."
The Scot's final game in charge after more than 26 years at the club
