Gerardo Martino's side continued their unbeaten start to the Liga campaign as Barca saw off the challenge of Real Madrid on Saturday with a 2-1 victory at Camp Nou in the marquee fixture.
A goal in either half from Neymar and Alexis Sanchez put Barcelona into a commanding lead before Jese Rodriguez's consolation effort for Carlo Ancelotti's side in injury time.
That result took the Catalan giants' record to nine wins and one draw from their 10 La Liga fixtures, meaning the defending champions head into Tuesday's game top of the table by one point from Atletico Madrid and six clear of Real.
The likes of Alexis, Pedro and Carlos Puyol were all named on the bench against Real and Martino could utilise his squad in order to keep them fresh, with a league clash against Espanyol on Friday on the horizon.
Key to Barca's success could be the form of Brazilian Neymar after his starring role in his first Clasico appearance, when the 21-year-old scored to take his Liga tally to three goals this season.
Luis Enrique's side have endured a difficult start to the season and sit in 16th position with just nine points from 10 games.
Celta, though, will be buoyed by their 5-0 rout of Malaga on Saturday, a victory that ended a run of seven league games without a win, including four straight defeats prior to facing Bernd Schuster's side.
