The FFF said on its website that Manchester City's Nasri was suffering from a knee injury that ruled him out of Friday's game against the U.S. and Tuesday's match against Belgium, both being played at the Stade de France.
Nasri, however, was not coach Laurent Blanc's only concern.
"We still have some little problems," he told reporters at France's training camp in the outskirts of Paris on Tuesday.
"[The knee injury] is a tricky one that he picked up while playing," Blanc said hours before Nasri pulled out.
Newcastle United holding midfielder Yohan Cabaye and Olympique Marseille forward Loic Remy have groin problems, while Chelsea winger Florent Malouda has a thigh injury.
"We'll assess the situation tonight or tomorrow morning and we will then see if we need to reinforce the squad," said Blanc, who confirmed Eric Abidal would join the squad only on Thursday after reaching an agreement with Barcelona coach Pep Guardiola.
Under the terms of the agreement, defender Abidal will sit on the bench for Barca's King's Cup match on Wednesday before joining the French squad.
"But he won't play France v USA," said Blanc.
France continue their preparations for Euro 2012 with a friendly against Germany in Bremen in February.
