Sevilla President Jose Maria del Nido slammed the structure of the Spanish football league and said that only two teams could win the title after Real and Barca won their opening matches of the season 6-0 and 5-0 respectively last weekend.
"If he doesn't like this one, why doesn't he look for another," Ramos told reporters as he joined up for international duty with the Spain squad on Wednesday.
Del Nido described the league as "third-world" and "rubbish" because of the way Barca and Real took half of the total revenue earned from television rights, stirring up a debate on the state of Spanish football.
Villarreal president Fernando Roig, whose side were thrashed 5-0 at the Nou Camp on Monday, said Real and Barca were "killing Spanish football" and that changes had to be made.
"He is one of the people fighting to change the competition and we support him," Negredo told reporters.
"It shouldn't just be about two teams. It's all about the income the clubs earn to be able to strengthen their squads and other teams can't do this. It's the main thing I would change."
"The superiority of Real and Barca is brutal," he said. " "I agree with the president that this has to change, to level things out."
"They need to find a solution for the league," Valencia's Argentine midfielder Pablo Piatti told reporters. "There is an enormous economic difference, and Real and Barca are a long way ahead of the rest."
European and Spanish champions Barca and Real, the world's two richest clubs by revenue, operated on budgets four times the size of their nearest rivals last season.
"We have an extraordinary league with great players," he told a news conference on Wednesday.
"We have a national team who are world and European champions, the Under-21s are European champions, as are the Under-19s. This is, along with our great league, Spanish football."
