The striker was one of the standout performers as Antonio Conte's men picked up victories in a friendly against Netherlands followed by their opening Euro 2016 qualifier in Norway.
A goal in the second of those fixtures will have done Zaza's chances of retaining a place in the national setup the world of good, but his domestic form could prove just as important to that end.
The 23-year-old found the net in the season-opening 1-1 draw with Cagliari to initially catch Conte's eye, and his goals will undoubtedly prove crucial as Sassuolo bid to preserve their top-flight status.
Along with Juventus loanee Domenico Berardi, who netted 16 league goals last term, Zaza forms part of a Sassuolo attacking line that is likely to cause problems for some, but Inter will be keen to get a first win under their belt at San Siro on Saturday.
Walter Mazzarri's men were held to a goalless draw at Torino in their first match of the season - a fixture Nemanja Vidic will want to forget after conceding a penalty and receiving a late red card.
Marco van Ginkel - on loan from Chelsea - could be among the debutants as Milan travel to Parma on Sunday, while Micah Richards will be one of those looking to make a first appearance for Fiorentina after making a temporary switch from Manchester City. The Florence club are at home to Genoa.
Roma have been bolstered by the arrivals of Jose Holebas and Mapou Yanga-Mbiwa since their 2-0 win over Fiorentina, and could hand the duo debuts at Empoli.
Verona and Palermo round of the second round of fixtures at Stadio Marc'Antonio Bentegodi, in a match which could see Javier Saviola make his debut for the hosts.
