The Germans have never beaten Italy at a major championship, famously losing the 2006 World Cup semi-final on home soil to the eventual victors, but they are favourites to progress this time having won all four matches so far in Poland and Ukraine.
However, they have yet to come up against a midfielder with the class of Pirlo, who has scored or set up all Italy's goals here and produced a wonderful display in the quarter-final with England before scoring the cheekiest of penalties.
The dinked spot-kick in the shootout showed the 33-year-old is far from over the hill as some had wondered and instead is revelling in a confident spell of form which pundits already think could lead him to be named player of the tournament.
"Pirlo's penalty even surprised me," Italy coach Cesare Prandelli told reporters. "Then when he said that he took it like that to put pressure on the English I realised that there is always something to learn from champions like him."
If anyone can stop his raking passes in Warsaw, it is the dynamic Schweinsteiger, who seems to cover every blade of grass and epitomises Germany's youthful yet experienced side of all-round talents.
Schweinsteiger suffered an ankle injury in February and it is still hampering his movement but the team is hopeful he can play after missing two days of training to rest.
"Bastian is a world class player and he is a leading player in our team," said playmaker Mesut Ozil. "I hope he can be fit in time for the game."
Otherwise Germany are fully fit and at full strength with coach Joachim Low widely expected to bring back at least two of the front three he surprisingly rested in the 4-2 quarter-final win over Greece.
Main striker Mario Gomez is likely to come back in for Miroslav Klose given his extra bulk against a wily Italian defence while Lukas Podolski and Thomas Muller will also be hoping for recalls.
Italy centre-half Giorgio Chiellini is back in training after missing the England game with a thigh problem and could feature while Prandelli has niggles to Daniele De Rossi and Ignazio Abate to worry about and right-back Christian Maggio's suspension.
Italy created reams of chances in the goalless 120 minutes against England and their lack of a finishing touch will haunt them if it continues in the Polish capital.
Prandelli seems to be leaning towards giving Mario Balotelli another chance despite his quarter-final misses.
"Mario was always in the moves that counted," the coach said while acknowledging Germany were favourites to join Spain and Portugal in the July 1 final in Kiev.
"They are some years ahead of us. After the 2006 World Cup they focused on youth and now they have a great squad."
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