Argentina booked a quarter-final clash against Venezuela following a comfortable 3-0 win over Bolivia in the Copa America Centenario on Tuesday.
First-half goals from Erik Lamela, Ezequiel Lavezzi and Victor Cuesta sealed the win, confirming top spot in Group D with nine points.
Argentina will now face Venezuela in the last eight of the special-edition centenary tournament, while Chile meet Mexico.
With their spot in the quarter-finals already confirmed, Gerardo Martino elected to make six changes from the line-up that defeated Panama 5-0, but that did not mean it was a weakened team.
The likes of Sergio Aguero, Lavezzi and Lamela all came into the side, and it was the latter who got things going in the 13th minute.
Bolivia conceded a foul in a dangerous area and Lamela's free-kick took a heavy deflection off Yasmani Duk, beating Carlos Lampe for just his second international goal.
It took Argentina less than two minutes to double their lead, with Lavezzi converting a loose ball in the area after Gonzalo Higuain had his shot saved by Lampe.
Lavezzi capitalised on a blocked shot and played in a low cross for Cuesta, and the Independiente man stretched to get the crucial touch.
Higuain almost made it 4-0 heading into half-time but he had his shot blocked, before Messi was introduced in place of the Napoli striker for the second period.
Messi was immediately busy, much to the delight of the crowd, and had a curling free-kick on the hour-mark just miss.
That did not stop them dominating possession, however, with Bolivia struggling to get a touch of the ball in their own half, let alone in the opposition's.
