Pearson's men have made a promising start to life in the Premier League having taken five points from their first four games, recording a first top-flight win for 10 years with a 1-0 victory at Stoke City last weekend.
United head to the King Power Stadium with the same total, but should pose a far more imposing test for Leicester after showing signs of a recovery from a poor start under Louis van Gaal with an impressive 4-0 demolition of QPR last Sunday - the Dutchman's maiden competitive triumph since taking over from David Moyes.
Angel di Maria was the man of the match, demonstrating why United paid a British-record fee of £59.7million to bring him to Old Trafford with an imperious midfield display.
"Man United have made their intentions clear this summer," Pearson said. "[It is] an opportunity for our players to face a very good side.
"Internally we expect to maximise our qualities. Every game in the Premier League is tough but we play with positive intent."
Schmeichel's recovery means that Matthew Upson (ankle) will be Leicester's only injury absentee, although on-loan United midfielder Nick Powell is ineligible to play against his parent club.
For Van Gaal the main selection issue surrounds whether to start Falcao – signed on a season-long loan from Monaco on transfer deadline day – after the United forward line displayed ruthless potency in the dismantling of QPR with the Colombian on the bench for much of the encounter.
The Dutchman suggested an out-of-form Van Persie would make way for Falcao should he be included from the start, after claiming Rooney had "more privileges" as captain.
Van Gaal's options in reserve are limited by a number of injures, particularly in midfield, where Marouane Fellaini and Michael Carrick remain on the sidelines with ankle problems.
