The four-time FIFA Ballon d'Or winner has tormented Almeria in the past and enters the clash on the brink of more goalscoring history.
Messi netted both goals in Barcelona's 2-0 UEFA Champions League win at Ajax on Wednesday - a result that sealed their progression to the competition's last 16.
The Argentina star's brace saw him equal the all-time record for goals in Europe's premier club competition. Messi has now scored 71 times in the Champions League, equalling the mark set by Real Madrid legend Raul.
Messi also sits just one adrift of the all-time La Liga scoring record set by Telmo Zarra (251 goals) - and history suggests this weekend could be the time he surpasses that mark.
The 27-year-old has scored in his last six matches against Almeria - netting 11 goals in the process.
A hat-trick followed in an 8-0 romp in November of the same year, while he chipped in with a double in a Copa del Rey win against the same opponents just over two months later.
Messi's scoring run has continued since, and he netted in both matches last term - clashes that ended in 2-0 and 4-1 wins to the Catalan giants.
Luis Enrique has one of the most mouth-watering forward lines ever assembled in world football and if Suarez can gel with his new team-mates quickly, Barca will be sure to mount a serious title threat.
Almeria have also failed to win any of their five home fixtures in La Liga this season.
