Diego Simeone's men sit third in the Spanish top flight, two points adrift of second-placed Barcelona and three points off city rivals and leaders Real Madrid.
However, Atletico's title charge has waned in recent weeks as they have picked up just one win from their last four league fixtures, while they also conceded a late equaliser to miss out on victory against Real on Sunday.
Saturday's trip to Vigo marks the beginning of a series of very winnable fixtures for the men from the Spanish capital, who face Espanyol, Real Betis and Granada before the end of March.
"They're a brilliant team, they're competing against Real Madrid and Barcelona for La Liga, which gives them enormous merit," he is quoted as saying by Faro De Vigo. "We've got to be very careful and focused.
"We need to show more intensity than they do, because if you're not intense enough against a great team like them, you've no chance.
"In the end though, it's 11 against 11 and even though we know it's going to be really difficult, we’ll be going out there to win, even if we can grab it in the final minute."
Atleti are without full-back Javier Manquillo (neck), who has taken his first steps towards making a return to training, while defender Rafinha (toe) is a doubt for the hosts and forward Mario Bermejo (thigh) could be back in contention.
