Arsenal striker Robin van Persie is likely to feature against Blackburn Rovers on Saturday after passing a fitness test on the knee he injured playing for Netherlands.
"He's alright. He will be in the squad," manager Arsene Wenger told reporters after Van Persie suffered the injury in the 5-3 win over Hungary in a Euro 2012 qualifier.
"It was a kick on his knee but he had a test this morning and felt alright," added Wenger. "If he has no reaction overnight he should be OK."
Vidic was injured in last month's FA Cup quarter-final against Arsenal and missed United's Champions League win over Olympique Marseille and Premier League victory against Bolton Wanderers.
His defensive partner Rio Ferdinand is back in training but will not be available and neither will fellow defenders Rafael, Wes Brown and John O'Shea.
Chelsea's only concerns ahead of the visit to Stoke City on Saturday are minor knocks to strikers Fernando Torres and Salomon Kalou suffered during the international break.
Spain's Torres and Ivory Coast's Kalou have only done light training over the past two days and might be left on the bench.
Manchester City striker Mario Balotelli will return to the squad for Sunday's home match against Sunderland after being dropped for disciplinary reasons.
