Barca midfielder Iniesta was among the starting XI that suffered a 1-0 defeat at Vicente Calderon on Wednesday, as Koke's fifth-minute volley ensured a 2-1 aggregate win for Atleti, which denied the Catalans a seventh consecutive appearance in the Champions League semi-finals.
The visitors had opportunities to level matters, with the likes of Lionel Messi, Neymar and Xavi all seeing chances go begging, but Iniesta conceded Atleti exerted more pressure in the opening stages and were rewarded for their efforts.
The Spain international has now set his sights on overhauling Atleti at the top of La Liga, while also pointing to Wednesday's Copa del Rey final with rivals Real Madrid as an ideal opportunity to bounce back.
"Atletico deserved to go through because they took advantage of their chances," Iniesta told Barcelona's official website. "Like in the first 20 minutes, they pressured us and they took advantage. We tried to score until the end of the game.
"The Champions League is a very good competition and it's a shame that we didn't make the semi-finals. There aren't many league games left to win the title and we have a final in Granada this weekend and on Wednesday in the Cup."
Full-back Jordi Alba echoed Iniesta's comments, while also lamenting the fact Barca were unable to break down a stubborn Atleti rearguard.
He added: "They were the better team in the opening minutes and after that we took control of the match, but we didn't know how to get into their area.
"It's very difficult to beat a rival (that plays this way), now we have to win the Liga and the Copa del Rey.
"After 20 minutes, the intensity was the same for both teams. We have to forget about this game and start over. We don't like to lose these games, especially in a competition like this one."
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