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Barcelona defender Adriano will miss this weekend's Clasico with a hamstring injury.
The defending Liga champions host arch rivals Real Madrid at Camp Nou on Saturday as they aim to further cement their grip on top spot.
Luis Enrique's men are nine points ahead of Atletico Madrid, with Zinedine Zidane's Madrid side a point further back in third.
Barca won November's reverse fixture at the Santiago Bernabeu 4-0 thanks in part to a double from Luis Suarez.
