Balotelli pulled up during training on Monday but flew with the squad to their Polish base on Tuesday.
"Balotelli has an issue with his abductor muscle like (right-back Christian) Maggio but it shouldn't be a problem," Prandelli told a news conference.
Asked if the temperamental forward would be ready to face holders Spain in Gdansk, Prandelli added: "Yes, yes absolutely yes."
Italy have been hit by a number of injuries in the runup to the tournament and defender Andrea Barzagli could yet be ruled out of the event in Poland and Ukraine because of a calf problem.
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