Lionel Messi netted a hat-trick in Barcelona's 4-0 La Liga win at Deportivo La Coruna, while leaders Real Madrid also won on Sunday.
Much attention prior to Barca's visit to the Riazor had been focused on discussions over Messi's future, following comments he made prior to Monday's FIFA Ballon d'Or ceremony.
Messi - beaten to the award by Cristiano Ronaldo - fuelled further speculation by stating "I don't know where I'll be next year" at the gala event in Zurich.
The Argentinian then rounded off a free-flowing team move in the 33rd minute before capping his 30th Barca hat-trick just after the hour mark with a fierce low drive into the bottom-right corner.
A late Sidnei own goal made it 4-0 to Barca, who remain one point adrift of Carlo Ancelotti's Real Madrid.
Granada, bottom of the league and without a permanent coach following Joaquin Caparros' departure on Friday, made a bright start but their good work was undone 11 minutes before the break when Abdoul Sissoko fouled Diego Godin in the penalty area.
Mandzukic was replaced by Garcia six minutes from time, and Diego Simeone's change paid dividends four minutes later as the midfielder headed home Arda Turan's cross from the right to wrap up the three points.
And Elche edged Levante 1-0, with Jonathas' 12th-minute strike proving crucial. Levante had David Navarro sent off in the sixth minute.
