Southampton, runners-up in last season's EFL Cup, have been drawn at home to Championship side Wolves in the second round of the 2017-18 competition, while Blackburn Rovers host local rivals Burnley.
Saints lost out in a thrilling 3-2 defeat to Manchester United at Wembley in February last season despite Marco Gabbiadini's double.
Lancashire rivals Blackburn and Burnley will renew acquaintances at Ewood Park in a fixture playfully dubbed locally as 'T'el Clasico', with their last meeting having coming in the Championship during the 2015-16 season, with the Clarets running out 1-0 victors on that occasion.
The teams that progress from the 25 ties and move into the third round will be joined by England's seven representatives playing in Europe this season.
: Round Two draw Here it is, in full... August 10, 2017
