Muamba, 24, collapsed in an FA Cup quarter-final against Spurs in London on March 17 and his heart stopped working on its own for 78 minutes. He came out of hospital two weeks ago after a remarkable recovery.
"If Fabrice is fit and well for that then I think the game against Tottenham would be a great opportunity because of the events that took place at White Hart Lane," Bolton manager Owen Coyle told British media on Monday.
"It would give a chance for everybody to see how well he is doing and it would also give him a chance to thank both sets of fans, who were magnificent on the night, and the Tottenham players.
"The concern they [Tottenham players] showed for Fabrice that night was remarkable."
Coyle's side are currently in 18th, level on 34 points with Queens Park Rangers who are outside the relegation zone thanks to a superior goal difference. Wigan Athletic and Aston Villa sit above them on 37 points.
