Uruguay: Penarol punish eight-man Tacuarembo
A defender was taken to hospital with concussion and a goalkeeper suffered suspected knee cartilage damage in Universidad de Chile's 3-3 draw with Santiago Wanderers.
Frustration got the better of Tacuarembo who had three players sent off late in their 3-1 loss to Clausura championship leaders Penarol.
Penarol, who have taken a maximum 12 points from their four matches, had already settled the result when midfielder Claudio Innella was shown a red card for a violent foul and defenders Carlos Dutra and Jose da Silva were dismissed for second bookings.
Striker Antonio Pacheco scored twice in the first half to take his tally to six. He had to take a 32nd-minute penalty twice because goalkeeper Jonny da Silva, who saved it, was ruled to have moved early. Substitute Diego Alonso scored their third in the 78th.
Jorge Ramirez scored a first-half hat-trick including two penalties as Central Espanol upset Defensor Sporting 4-3 away.
Striker Sergio Blanco scored six minutes from the start and six from the end to give champions Nacional a 2-0 win over Liverpool that leaves them five points off the pace.
Chile's two most popular clubs, Colo Colo and Universidad de Chile, were held to draws in the Apertura championship.
Moises Villarroel volleyed a brilliant 83rd-minute equaliser from 30 metres to give Santiago Wanderers a 3-3 draw with Universidad de Chile, who had led 3-1 with 19 minutes to go.
Wanderers defender Agustin Parra was concussed in a collision with his own goalkeeper David Reyes after 17 minutes and had to be taken to hospital.
Universidad's keeper Miguel Pinto, likely to get a place in Chile's World Cup squad and just back from injury, suffered a twinge in a knee cartilage and did not reappear for the second half. He was due to have tests on Monday to see if he needed surgery.
Colo Colo needed an equaliser from Paraguayan forward Cristian Bogado eight minutes from time to salvage a 2-2 draw at home against Nublense.
Union Espanola lead with 11 points from five matches after a 2-1 away win over Huachipato.
Promoted Sport Colombia scored twice in the last four minutes to upset title holders Nacional 2-1 away in the Apertura championship.
Cerro Porteno, winners of last year's Apertura, beat Trinidense 2-1 away to go top with a maximum nine points.
Match official Cesar Franco was shot in the leg as he was mugged close to his home last week and was unable to take his position as linesman in the match between Tacuary and Libertad, he told the radio programme Penalty Spot.
Roberto Gamarra scored twice in Libertad's 4-0 win.
America ended a run of 11 matches without victory by beating champions Independiente Medellin 1-0 with an own goal by defender Leiton Jimenez in the 83rd minute. Midfielder Mahler Moreno missed a penalty for Medell