Borussia Dortmund head coach Peter Bosz is aware his side must beat APOEL to keep their Champions League hopes alive on Tuesday.
Bundesliga leaders Dortmund are away to APOEL in Nicosia, having lost their opening two Group H fixtures.
"We've lost two times and we're here to win," Bosz told reporters. "But APOEL need a victory too."
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Schmelzer suffered an ankle injury against Freiburg on September 9, however, the 29-year-old made the trip to APOEL with his Dortmund team-mates.
"The fact that we brought Schmelle with us shows that he could well play," Bosz said. "The question is just whether he's able to start."
Schmelzer added: "We've not made a good start to our Champions League campaign and we absolutely want to win the match.
"We're aiming to win the two matches against APOEL. This would mean we'd be under less pressure."
