Messi missed Argentina's friendly victories over El Salvador and Ecuador due to swelling on his right foot, but Pique expects the 27-year-old to return for his club this weekend.
"I'm optimistic about Messi," said the defender. "I spoke with him and I think he'll be able to play at Balaidos [Celta's ground].
"But it depends on how he feels this week.
"It's the team doctors who have to decide. But from what I can gather, he'll be okay."
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