"He will be in the dugout with us," Vilanova's assistant Jordi Roura told a news conference on the eve of the game.
"He's the coach and his comeback is extremely important for us," added Roura who has been in charge in his absence.
Striker David Villa echoed Roura's views by saying: "It's always easier when the boss is there with us".
"Any absence is a blow in this competition but we'll do our best for them not to be noticed," added Villa.
"We won't change the way we play even though PSG are good on the counter-attack," he explained.
"We are used to playing against opponents who bank on defence but I don't think they will just wait in their half - they will try to do more than that."
"He's a great player and we'll have to keep an eye on him at all times," added the assistant coach.
"The Milan game showed us what not to do," Roura said. "We have to put in 100 percent in terms of a physical performance and in terms of intensity."
