Arsenal will face Liverpool in a mouth-watering clash on the opening day of the 2016-17 Premier League season, while Jose Mourinho's Manchester United are at AFC Bournemouth.
New Chelsea boss Antonio Conte will welcome West Ham to Stamford Bridge for a massive London derby to start the new season, while Everton are at home to last season's runners-up Tottenham in another standout fixture.
Leicester City open the defence of their title away to newly promoted Hull City, while Pep Guardiola's first league game in charge of Manchester City comes at home to Sunderland.
Burnley's return to the top-flight will see them take on Swansea City, while the other promoted outfit Middlesbrough are at home to Stoke City.
There will not be long to wait for the first Manchester derby between Mourinho and Guardiola, which takes place on September 10 at Old Trafford – the fourth week of the season – with the Etihad Stadium meeting pencilled in for February 25.
Mourinho's first return to former club Chelsea comes at Stamford Bridge on October 22, with the return at Old Trafford on April 15.
A difficult start to the season for Arsene Wenger's men will also see them take on Chelsea in their sixth game of the season on September 24.
The meetings between the Gunners and United, which will see Wenger and Mourinho renew their rivalry, are on November 19 at Old Trafford and on May 6 in a potentially decisive match at Emirates Stadium.
AFC Bournemouth v Manchester United
Arsenal v Liverpool
Burnley v Swansea City
Chelsea v West Ham
Crystal Palace v West Brom
Everton v Tottenham
Hull City v Leicester City
Manchester City v Sunderland
Middlesbrough v Stoke City
Southampton v Watford
