Mathijsen again trained on his own for almost the entire session on Wednesday but he could only jog gingerly and did not touch the ball.
Van Marwijk told a news conference: "I am willing to take a risk but we will see in the next two days what will happen."
Wilfred Bouma, who only made the squad at the last minute, is being tipped as a potential replacement for Mathijsen given his greater experience than the other contenders.
Mathijsen was injured during the 2010 World Cup finalists' 2-1 loss to Bulgaria in a friendly last month.
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