Colchester turn to academy manager Humes
The League One club parted company with Dunne on Monday after just short of two years at the helm, with Colchester sitting second-bottom of League One.
Humes was announced as his successor within a matter of hours and will be in charge for Saturday's trip to Walsall.
The 48-year-old moved to Colchester as head of youth in 2009.
United, who are in their seventh consecutive season in the third tier, have lost five matches in a row in all competitions.